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092    615.1 
245 10 Pharmaceutical Sciences CD|h[Computer file] 
260    London :|bWiley,|cc2007 
300    1 computer optical disc (4 3/4 in.) 
500    A CD-ROM containing over 160 papers from leading journals 
       in the Pharmaceutical Sciences, issued as an introduction 
       to Wiley resources in the subject. Contents listing 
       includes selected content only. 
505  0 [Archive der Pharmazie] |tSynthesis of tyrosinase 
       inhibitory Kojic Acid derivative -- |tNovel Pirfenidone 
       Analogues: Synthesis of Pyridin-2-ones for the Treatment 
       of Pulmonary Fibrosis -- |tPotent Inhibitory Effects of 
       Resveratrol Derivatives on progression of Prostate Cancer 
       Cells -- |tRandom Chemistry as a New Tool for the 
       Generation of Small-Compound Libraries -- |tRhodopsin: A 
       Structural Primer for G-Protein Coupled Receptors. 
505  0 [Biomedical Chromatography] A|treview of chromatographic 
       methods for the assessment of phospholipids in biological 
       samples -- |tComprehensive multi-dimensional liquid 
       chromatographic separation in biomedical and 
       pharmaceutical analysis: a review -- |tApplicability of 
       bioanalysis of multiple analytes in drug discovery and 
       development: review of select case studies including assay
       development considerations -- |tSome remarks on 
       characterization and application of stationary phases for 
       RP-HPLC determination of biologically important compounds 
       -- |tAnalysis of five HMG-CoA reductase inhibitors - 
       atorvastatin, lovastatin, pravastatin, rosuvastatin and 
       simvastatin: pharmacological, pharmacokinetic and 
       analytical overview and development of a new method for 
       use in pharmaceutical formulations analysis and in vitro 
       metabolism studies. 
505  0 [Biometrical Journal] |tSample Size Recalculation in 
       Internal Pilot Study Designs: A Review -- A|tRegulatory 
       View on Adaptive/Flexible Clinical Trial Design -- An
       |tOverview of Statistical Approaches for Adaptive Designs 
       and Design Modifications -- |tApplication of Adaptive 
       Designs - a Review -- |tFDA's Critical Path Initiative: A 
       Perspective on Contributions of Biostatistics. 
505  0 [Biopharmaceutics & Drug Disposition] |tDrug Disposition 
       in Three Dimensions: An Update on Stereoselectivity in 
       Pharmacokinetics -- |tProfiling In Vitro Drug Release from
       Subcutaneous Implants: A Review of Current Status and 
       Potential Implications on Drug Product Development -- 
       |tApparent Active Transport of MDMA is not Mediated by P-
       glycoprotein: A Comparison with MDCK and Caco-2 Monolayers
       -- |tResveratrol is Efficiently Glucuronidated by 
       UDPGlucuronosyltransferases in the Human Gastrointestinal 
       Tract and in Caco-2 Cells -- |tIn Vitro Metabolism of 
       Ciclesonide in Human Lung and Liver Precision-cut Tissue 
       Slices. 
505  0 [Biotechnology Journal] |tManufacturing of recombinant 
       therapeutic proteins in microbial systems -- 
       |tAntimalarial drugs - host targets (re)visited -- 
       |tCancer immunotherapy -- |tElectric field driven jetting:
       an emerging approach for processing living cells -- 
       |tEssential fatty acids: biochemistry, physiology and 
       pathology. 
505  0 [Cell Biochemistry and Function] A|tcentral role of eNOS 
       in the protective effect of wine against metabolic 
       syndrome -- |tAntioxidative and anti-diabetic effects of 
       amaranth (Amaranthus esculantus) in streptozotocin-induced
       diabetic rats -- |tTissue factor upregulation drives a 
       thrombosis-inflammation circuit in relation to 
       cardiovascular complications -- |tInvestigation of protein
       oxidation and lipid peroxidation in patients with 
       rheumatoid arthritis -- |tRole of fatty acids in the 
       transition from anaerobic to aerobic metabolism in 
       skeletal muscle during exercise. 
505  0 [Chemistry and Biodiversity] A|tBroad Diversity of 
       Volatile Carboxylic Acids, Released by a Bacterial 
       Aminoacylase from Axilla Secretions, as Candidate 
       Molecules for the Determination of Human-Body Odor Type --
       |tInfrared Spectroscopy as a Tool for Chemotaxonomic 
       Investigations within the Achillea millefolium Group -- 
       |t5-(Pyrrolidin-2-yl)-1H-tetrazole and 5-[(Pyrrolidin-2-
       yl)methyl]-1Htetrazole: Proline Surrogates with Increased 
       Potential in Asymmetric Catalysis -- |tSynthesis and 
       Biological Evaluation of New Quinazoline and Cinnoline 
       Derivatives as Potential Atypical Antipsychotics -- |tDNA 
       Containing Side Chains with Terminal Triple Bonds: Base-
       Pair Stability and Functionalization of Alkynylated 
       Pyrimidines and 7-Deazapurines. 
505  0 [Contrast Media and Molecular Imaging] |tFirst in vivo MRI
       assessment of a self-assembled metallostar compound 
       endowed with a remarkable high field relaxivity -- 
       |tCellular labeling with Gd(III) chelates: only high 
       thermodynamic stabilities prevent the cells acting as 
       'sponges' of Gd3+ ions -- |tComparative study of the 
       physicochemical properties of six clinical low molecular 
       weight gadolinium contrast agentsy -- An|tHPLC/mass 
       spectrometry platform for the development of multimodality
       contrast agents and targeted therapeutics: prostate-
       specific membrane antigen small molecule derivatives -- 
       |tPharmacokinetic and in vivo evaluation of a self-
       assembled gadolinium(III)-iron(II) contrast agent with 
       high relaxivity. 
505  0 [Drug Development Research] |tBiopolymer Albumin for 
       Diagnosis and in Drug Delivery -- The|tClinical 
       Pharmacology of Therapeutic Monoclonal Antibodies -- 
       |tTargeted Nanoparticles for Detecting and Treating Cancer
       -- |tCommercial Manufacturing Scale Formulation and 
       Analytical Characterization of Therapeutic Recombinant 
       Antibodies -- The|tMedicinal Chemistry of Tea. 
505  0 [Journal of Applied Toxicology] -- A|tGood Practice Guide 
       to the Administration of Substances and Removal of Blood, 
       Including Routes and Volumes -- |tMetalloestrogens: an 
       emerging class of inorganic xenoestrogens with potential 
       to add to the oestrogenic burden of the human breast -- A
       |tclinical flow cytometric biomarker strategy: validation 
       of peripheral leukocyte phospholipidosis using Nile red --
       |tToxicology of fluoroacetate: a review, with possible 
       directions for therapy research -- |tHair analysis by GC/
       MS/MS to verify abuse of drugs. 
505  0 [Journal of Mass Spectrometry] |tAmbient mass spectrometry
       using desorption electrospray ionization (DESI): 
       instrumentation, mechanisms and applications in forensics,
       chemistry, and biology -- The|tOrbitrap: a new mass 
       spectrometer -- |tStructurally diagnostic ion/molecule 
       reactions: class and functional-group identification by 
       mass spectrometry -- |tDetecting and characterizing 
       reactive metabolites by liquid chromatography/tandem mass 
       spectrometry -- |tIn vivo metabolite detection and 
       identification in drug discovery via LC-MS/MS with data-
       dependent scanning and postacquisition data mining. 
505  0 [Journal of Molecular Recognition] |tMolecular imprinting 
       science and technology: a survey of the literature for the
       years up to and including 2003 -- |tSurvey of the year 
       2004 commercial optical biosensor literature -- 
       |tIsothermal titration calorimetry and differential 
       scanning calorimetry as complementary tools to investigate
       the energetics of biomolecular recognition -- |tExpression
       of heterologous proteins in Pichia pastoris: a useful 
       experimental tool in protein engineering and production --
       |tAdvances in membrane receptor screening and analysis. 
505  0 [Journal of Pharmaceutical Sciences] |tAnalytical 
       Techniques for Quantification of Amorphous / Crystalline 
       Phases in Pharmaceutical Solids -- |tCell Adhesion 
       Molecules for Targeted Drug Delivery -- |tEnzymes Involved
       in the Bioconversion of Ester-Based Prodrugs -- 
       |tFormulation Considerations for Proteins Susceptible to 
       Asparagine Deamidation and Aspartate Isomerization -- 
       |tEffect of Food Intake on the Oral Absorption of Poorly 
       Water-Soluble Drugs: In Vitro Assessment of Drug 
       Dissolution and Permeation Assay System. 
505  0 [Molecular Nutrition and Food Research] The|tdifferential 
       role of prostaglandin E2 receptors EP3 and EP4 in 
       regulation of fever -- |tChemistry and biology of vitamin 
       E -- |tFood allergy --  |tHypercholesterolemia and 
       inflammation in atherogenesis: Two sides of the same coin 
       -- |tTea, obesity, and diabetes. 
505  0 [Pharmaceutical Statistics] |tReview of guidelines and 
       literature for handling missing data in longitudinal 
       clinical trials with a case study -- |tRequiring 
       'independent' statistical analyses for industry sponsored 
       trials? -- |tAdaptive designs for pivotal trials: 
       discussion points from the PSI Adaptive Design Expert 
       Group -- |tAdapting the sample size planning of a phase 
       III trial based on phase II data -- |tMethodological 
       issues with adaptation of clinical trial design. 
505  0  [Pharmacoepidemiology and Drug Safety: An International 
       Journal] |tResults from a rosuvastatin historical cohort 
       study in more than 45 000 Dutch statin users, a PHARMO 
       Study -- |tPharmDCardiovascular risk of selective 
       cyclooxygenase-2 inhibitors and other non-aspirin non-
       steroidal anti-inflammatory medications -- A|tsystematic 
       review of NSAIDs withdrawn from the market due to 
       hepatotoxicity: lessons learned from the bromfenac 
       experience -- |tMDFDA drug prescribing warnings: is the 
       black box half empty or half full? -- |tSensitivity 
       analysis and external adjustment for unmeasured 
       confounders in epidemiologic database studies of 
       therapeutics. 
505  0 [Phytotherapy Research] The|tEfficacy of Silybum marianum 
       (L.) Gaertn. (Silymarin) in the Treatment of Type II 
       Diabetes: A Randomized, Double-blind, Placebo-controlled, 
       Clinical Trial -- |tPotential Synergism of Natural 
       Products in the Treatment of Cancer -- |tAntioxidant 
       Activities of Some Lamiaceae Plant Extracts -- A|tReview 
       of the Bioactivity and Potential Health Benefits of 
       Peppermint Tea (Mentha piperita L.) -- |tAnti-influenza 
       Agents from Plants and Traditional Chinese Medicine. 
505  0  [QSAR and Combinational Science] |tData and Graph Mining 
       in Chemical Space for ADME and Activity Data Sets  -- 
       |tDock around the Clock - Current Status of Small Molecule
       Docking and Scoring -- |tOn Selection of Training and Test
       Sets for the Development of Predictive QSAR models -- 
       |tCurrent Status of Combinatorial and High-Throughput 
       Methods for Discovering New Materials and Catalysts -- The
       |tApplication of Microreactors in Combinatorial Chemistry.
505  0  [Rapid Communications in Mass Spectrometry] 
       |tPhosphopeptide quantitation using amine-reactive 
       isobaric tagging reagents and tandem mass spectrometry: 
       application to proteins isolated by gel electrophoresis --
       The|tuse of recently described ionisation techniques for 
       the rapid analysis of some common drugs and samples of 
       biological origin -- |tDesorption electrospray ionization 
       mass spectrometry: direct toxicological screening and 
       analysis of illicit Ecstasy tablets -- |tDesorption 
       electrospray ionization mass spectrometry for the analysis
       of pharmaceuticals and metabolites -- |tDevelopment of a 
       multi-target screening analysis for 301 drugs using a 
       QTrap liquid chromatography/tandem mass spectrometry 
       system and automated library searching. 
505  0  [Statistics in Medicine] A|tSimple Method of Sample Size 
       Calculation for Linear and Logistic Regression -- 
       |tTutorial in Biostatistics : An Introduction to 
       Hierarchical Linear Modelling -- |tDichotomizing 
       continuous predictors in multiple regression: a bad idea -
       - |tStatistical evaluation of biomarkers as surrogate 
       endpoints: a literature review -- |tTutorial in 
       Biostatistics Propensity Score Methods for Bias Reduction 
       in the Comparison of a Treatment to a Non-Randomized 
       Control. 
505  0  [The Quality Assurance Journal] |tBioanalytical Quality 
       Assurance: Concepts and Concerns -- |tTechnology-Driven 
       Forms of Quality Improvement and Technical Evolution -- 
       |tDevelopment of a Professional Quality Assurance Society 
       - The SQA Model -- |tInternational Marketing Applications 
       According to the ICH CTD Format: Comparison of Structure 
       and Document Requirements -- The|tRole of the Study 
       Director in GLP. 
590    30.00 
650  0 Pharmacology|vJournal articles. 
650  0 Pharmaceutical technology|vJournal articles. 
650  0 Pharmaceutical sciences|vJournal articles 
856 41 |uhttp://www.wiley.com|zLink to the COMPANION WEBSITE 
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