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245 10 Pharmaceutical Sciences CD|h[Computer file]
260 London :|bWiley,|cc2007
300 1 computer optical disc (4 3/4 in.)
500 A CD-ROM containing over 160 papers from leading journals
in the Pharmaceutical Sciences, issued as an introduction
to Wiley resources in the subject. Contents listing
includes selected content only.
505 0 [Archive der Pharmazie] |tSynthesis of tyrosinase
inhibitory Kojic Acid derivative -- |tNovel Pirfenidone
Analogues: Synthesis of Pyridin-2-ones for the Treatment
of Pulmonary Fibrosis -- |tPotent Inhibitory Effects of
Resveratrol Derivatives on progression of Prostate Cancer
Cells -- |tRandom Chemistry as a New Tool for the
Generation of Small-Compound Libraries -- |tRhodopsin: A
Structural Primer for G-Protein Coupled Receptors.
505 0 [Biomedical Chromatography] A|treview of chromatographic
methods for the assessment of phospholipids in biological
samples -- |tComprehensive multi-dimensional liquid
chromatographic separation in biomedical and
pharmaceutical analysis: a review -- |tApplicability of
bioanalysis of multiple analytes in drug discovery and
development: review of select case studies including assay
development considerations -- |tSome remarks on
characterization and application of stationary phases for
RP-HPLC determination of biologically important compounds
-- |tAnalysis of five HMG-CoA reductase inhibitors -
atorvastatin, lovastatin, pravastatin, rosuvastatin and
simvastatin: pharmacological, pharmacokinetic and
analytical overview and development of a new method for
use in pharmaceutical formulations analysis and in vitro
metabolism studies.
505 0 [Biometrical Journal] |tSample Size Recalculation in
Internal Pilot Study Designs: A Review -- A|tRegulatory
View on Adaptive/Flexible Clinical Trial Design -- An
|tOverview of Statistical Approaches for Adaptive Designs
and Design Modifications -- |tApplication of Adaptive
Designs - a Review -- |tFDA's Critical Path Initiative: A
Perspective on Contributions of Biostatistics.
505 0 [Biopharmaceutics & Drug Disposition] |tDrug Disposition
in Three Dimensions: An Update on Stereoselectivity in
Pharmacokinetics -- |tProfiling In Vitro Drug Release from
Subcutaneous Implants: A Review of Current Status and
Potential Implications on Drug Product Development --
|tApparent Active Transport of MDMA is not Mediated by P-
glycoprotein: A Comparison with MDCK and Caco-2 Monolayers
-- |tResveratrol is Efficiently Glucuronidated by
UDPGlucuronosyltransferases in the Human Gastrointestinal
Tract and in Caco-2 Cells -- |tIn Vitro Metabolism of
Ciclesonide in Human Lung and Liver Precision-cut Tissue
Slices.
505 0 [Biotechnology Journal] |tManufacturing of recombinant
therapeutic proteins in microbial systems --
|tAntimalarial drugs - host targets (re)visited --
|tCancer immunotherapy -- |tElectric field driven jetting:
an emerging approach for processing living cells --
|tEssential fatty acids: biochemistry, physiology and
pathology.
505 0 [Cell Biochemistry and Function] A|tcentral role of eNOS
in the protective effect of wine against metabolic
syndrome -- |tAntioxidative and anti-diabetic effects of
amaranth (Amaranthus esculantus) in streptozotocin-induced
diabetic rats -- |tTissue factor upregulation drives a
thrombosis-inflammation circuit in relation to
cardiovascular complications -- |tInvestigation of protein
oxidation and lipid peroxidation in patients with
rheumatoid arthritis -- |tRole of fatty acids in the
transition from anaerobic to aerobic metabolism in
skeletal muscle during exercise.
505 0 [Chemistry and Biodiversity] A|tBroad Diversity of
Volatile Carboxylic Acids, Released by a Bacterial
Aminoacylase from Axilla Secretions, as Candidate
Molecules for the Determination of Human-Body Odor Type --
|tInfrared Spectroscopy as a Tool for Chemotaxonomic
Investigations within the Achillea millefolium Group --
|t5-(Pyrrolidin-2-yl)-1H-tetrazole and 5-[(Pyrrolidin-2-
yl)methyl]-1Htetrazole: Proline Surrogates with Increased
Potential in Asymmetric Catalysis -- |tSynthesis and
Biological Evaluation of New Quinazoline and Cinnoline
Derivatives as Potential Atypical Antipsychotics -- |tDNA
Containing Side Chains with Terminal Triple Bonds: Base-
Pair Stability and Functionalization of Alkynylated
Pyrimidines and 7-Deazapurines.
505 0 [Contrast Media and Molecular Imaging] |tFirst in vivo MRI
assessment of a self-assembled metallostar compound
endowed with a remarkable high field relaxivity --
|tCellular labeling with Gd(III) chelates: only high
thermodynamic stabilities prevent the cells acting as
'sponges' of Gd3+ ions -- |tComparative study of the
physicochemical properties of six clinical low molecular
weight gadolinium contrast agentsy -- An|tHPLC/mass
spectrometry platform for the development of multimodality
contrast agents and targeted therapeutics: prostate-
specific membrane antigen small molecule derivatives --
|tPharmacokinetic and in vivo evaluation of a self-
assembled gadolinium(III)-iron(II) contrast agent with
high relaxivity.
505 0 [Drug Development Research] |tBiopolymer Albumin for
Diagnosis and in Drug Delivery -- The|tClinical
Pharmacology of Therapeutic Monoclonal Antibodies --
|tTargeted Nanoparticles for Detecting and Treating Cancer
-- |tCommercial Manufacturing Scale Formulation and
Analytical Characterization of Therapeutic Recombinant
Antibodies -- The|tMedicinal Chemistry of Tea.
505 0 [Journal of Applied Toxicology] -- A|tGood Practice Guide
to the Administration of Substances and Removal of Blood,
Including Routes and Volumes -- |tMetalloestrogens: an
emerging class of inorganic xenoestrogens with potential
to add to the oestrogenic burden of the human breast -- A
|tclinical flow cytometric biomarker strategy: validation
of peripheral leukocyte phospholipidosis using Nile red --
|tToxicology of fluoroacetate: a review, with possible
directions for therapy research -- |tHair analysis by GC/
MS/MS to verify abuse of drugs.
505 0 [Journal of Mass Spectrometry] |tAmbient mass spectrometry
using desorption electrospray ionization (DESI):
instrumentation, mechanisms and applications in forensics,
chemistry, and biology -- The|tOrbitrap: a new mass
spectrometer -- |tStructurally diagnostic ion/molecule
reactions: class and functional-group identification by
mass spectrometry -- |tDetecting and characterizing
reactive metabolites by liquid chromatography/tandem mass
spectrometry -- |tIn vivo metabolite detection and
identification in drug discovery via LC-MS/MS with data-
dependent scanning and postacquisition data mining.
505 0 [Journal of Molecular Recognition] |tMolecular imprinting
science and technology: a survey of the literature for the
years up to and including 2003 -- |tSurvey of the year
2004 commercial optical biosensor literature --
|tIsothermal titration calorimetry and differential
scanning calorimetry as complementary tools to investigate
the energetics of biomolecular recognition -- |tExpression
of heterologous proteins in Pichia pastoris: a useful
experimental tool in protein engineering and production --
|tAdvances in membrane receptor screening and analysis.
505 0 [Journal of Pharmaceutical Sciences] |tAnalytical
Techniques for Quantification of Amorphous / Crystalline
Phases in Pharmaceutical Solids -- |tCell Adhesion
Molecules for Targeted Drug Delivery -- |tEnzymes Involved
in the Bioconversion of Ester-Based Prodrugs --
|tFormulation Considerations for Proteins Susceptible to
Asparagine Deamidation and Aspartate Isomerization --
|tEffect of Food Intake on the Oral Absorption of Poorly
Water-Soluble Drugs: In Vitro Assessment of Drug
Dissolution and Permeation Assay System.
505 0 [Molecular Nutrition and Food Research] The|tdifferential
role of prostaglandin E2 receptors EP3 and EP4 in
regulation of fever -- |tChemistry and biology of vitamin
E -- |tFood allergy -- |tHypercholesterolemia and
inflammation in atherogenesis: Two sides of the same coin
-- |tTea, obesity, and diabetes.
505 0 [Pharmaceutical Statistics] |tReview of guidelines and
literature for handling missing data in longitudinal
clinical trials with a case study -- |tRequiring
'independent' statistical analyses for industry sponsored
trials? -- |tAdaptive designs for pivotal trials:
discussion points from the PSI Adaptive Design Expert
Group -- |tAdapting the sample size planning of a phase
III trial based on phase II data -- |tMethodological
issues with adaptation of clinical trial design.
505 0 [Pharmacoepidemiology and Drug Safety: An International
Journal] |tResults from a rosuvastatin historical cohort
study in more than 45 000 Dutch statin users, a PHARMO
Study -- |tPharmDCardiovascular risk of selective
cyclooxygenase-2 inhibitors and other non-aspirin non-
steroidal anti-inflammatory medications -- A|tsystematic
review of NSAIDs withdrawn from the market due to
hepatotoxicity: lessons learned from the bromfenac
experience -- |tMDFDA drug prescribing warnings: is the
black box half empty or half full? -- |tSensitivity
analysis and external adjustment for unmeasured
confounders in epidemiologic database studies of
therapeutics.
505 0 [Phytotherapy Research] The|tEfficacy of Silybum marianum
(L.) Gaertn. (Silymarin) in the Treatment of Type II
Diabetes: A Randomized, Double-blind, Placebo-controlled,
Clinical Trial -- |tPotential Synergism of Natural
Products in the Treatment of Cancer -- |tAntioxidant
Activities of Some Lamiaceae Plant Extracts -- A|tReview
of the Bioactivity and Potential Health Benefits of
Peppermint Tea (Mentha piperita L.) -- |tAnti-influenza
Agents from Plants and Traditional Chinese Medicine.
505 0 [QSAR and Combinational Science] |tData and Graph Mining
in Chemical Space for ADME and Activity Data Sets --
|tDock around the Clock - Current Status of Small Molecule
Docking and Scoring -- |tOn Selection of Training and Test
Sets for the Development of Predictive QSAR models --
|tCurrent Status of Combinatorial and High-Throughput
Methods for Discovering New Materials and Catalysts -- The
|tApplication of Microreactors in Combinatorial Chemistry.
505 0 [Rapid Communications in Mass Spectrometry]
|tPhosphopeptide quantitation using amine-reactive
isobaric tagging reagents and tandem mass spectrometry:
application to proteins isolated by gel electrophoresis --
The|tuse of recently described ionisation techniques for
the rapid analysis of some common drugs and samples of
biological origin -- |tDesorption electrospray ionization
mass spectrometry: direct toxicological screening and
analysis of illicit Ecstasy tablets -- |tDesorption
electrospray ionization mass spectrometry for the analysis
of pharmaceuticals and metabolites -- |tDevelopment of a
multi-target screening analysis for 301 drugs using a
QTrap liquid chromatography/tandem mass spectrometry
system and automated library searching.
505 0 [Statistics in Medicine] A|tSimple Method of Sample Size
Calculation for Linear and Logistic Regression --
|tTutorial in Biostatistics : An Introduction to
Hierarchical Linear Modelling -- |tDichotomizing
continuous predictors in multiple regression: a bad idea -
- |tStatistical evaluation of biomarkers as surrogate
endpoints: a literature review -- |tTutorial in
Biostatistics Propensity Score Methods for Bias Reduction
in the Comparison of a Treatment to a Non-Randomized
Control.
505 0 [The Quality Assurance Journal] |tBioanalytical Quality
Assurance: Concepts and Concerns -- |tTechnology-Driven
Forms of Quality Improvement and Technical Evolution --
|tDevelopment of a Professional Quality Assurance Society
- The SQA Model -- |tInternational Marketing Applications
According to the ICH CTD Format: Comparison of Structure
and Document Requirements -- The|tRole of the Study
Director in GLP.
590 30.00
650 0 Pharmacology|vJournal articles.
650 0 Pharmaceutical technology|vJournal articles.
650 0 Pharmaceutical sciences|vJournal articles
856 41 |uhttp://www.wiley.com|zLink to the COMPANION WEBSITE